Principal Investigators

There are no clear guidelines on how patients with signs and symptoms of ischemia but not obstructive CAD should be treated. Together, UF Health and Cedars-Sinai researchers aim to determine whether intensive medical treatment will reduce adverse CV outcomes in these patients.

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Carl Pepine

Dr. Carl J. Pepine, M.D., MACC

Dr. Pepine is a professor emeritus of medicine, with clinical interests that include Ischemic heart disease, heart disease in women, cardiovascular cell therapy, preventive and genetic cardiology, cardiovascular disease, and hypertension and lipid disorders.


Eileen M. Handberg

Dr. Eileen M. Handberg, PhD, ARNP-BC, FACC

Dr. Handberg is a Research Professor of Medicine and Director of the Cardiovascular Clinical Trials Program in the Division of Cardiovascular Medicine. She also serves as an Institutional Review Board member.


Rhonda Cooper-DeHoff

Dr. Rhonda Cooper-DeHoff, Pharm.D., M.S., FAHA, FACC

Dr. Cooper-DeHoff is a Associate Professor in the Department of Pharmacotherapy and Translational Research, and the Department of Pharmaceutics in the College of Pharmacy, and in the Division of Cardiovascular Medicine, College of Medicine at the University of Florida.

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C Noel Bairey Merz

Dr. C Noel Bairey Merz, MD

The research of C. Noel Bairey Merz, MD, focuses on heart disease in women, preventive cardiology, coronary physiology/pathophysiology and advanced cardiac imaging, as well as alternative and complementary medicine approaches to heart disease.


Andre Rogatko

Dr. Andre Rogatko, PhD

The research of Andre Rogatko, PhD, focuses on using statistical methods to improve the design and analysis of clinical trials, genetic epidemiology, and risk prediction.


Janet Wei

Dr. Janet Wei, MD, FACC

Dr. Wei’s research interests include heart disease in women, cardiovascular disease prevention, and coronary vascular dysfunction. Her research includes the evaluation of coronary, carotid, and peripheral atherosclerosis using magnetic resonance imaging.